@m_idso thank you for the suggestion.
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Couple of notes on this card:
This user’s addition of ammonia is correct according to this video from KA:
https://www.khanacademy.org/test-prep/mcat/chemical-processes/proteins/v/alpha-amino-acid-synthesis
and Kaplan:
In the Strecker synthesis, one starts with an aldehyde, ammonium chloride (NH4Cl), and potassium cyanide (KCN) - the ammonium chloride serving as the source of ammonia.
In our card for Gabriel synthesis, we list all the reactants:
{{c1::Gabriel synthesis}} generates an amino acid from {{c2::potassium phthalimide}}, {{c2::diethyl bromomalonate}}, and {{c2::an alkyl halide}}.
I wonder if for consistency we should be doing the same for this card.
Another issue: The KA video above suggests that Strecker synthesis can occur using an aldehyde or ketone. Kaplan just states that an aldehyde is used. Have yet to see a question about this topic on UWorld. Non primary MCAT sources online seem to suggest a ketone can be used as well.
One thing that I think both the Gabriel Synthesis and Strecker synthesis cards are definitely currently lacking is that both produce a racemic mixture of L- and D-amino acid (Kaplan 10.2)
Action items:
- Aldehyde and ketone? or just aldehyde?
- Include all reactants to match depth provided by Gabriel synthesis card? (aldehyde/ketone/whatever we decide + Ammonia + KCN)
- Inclusion of racemic mixture of products?