[01.11.2025] Updated content, AnKing-MCAT/AnKingMed, ID 2778941

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@m_idso thank you for the suggestion. :slight_smile:

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Couple of notes on this card:

This user’s addition of ammonia is correct according to this video from KA:

https://www.khanacademy.org/test-prep/mcat/chemical-processes/proteins/v/alpha-amino-acid-synthesis

and Kaplan:
In the Strecker synthesis, one starts with an aldehyde, ammonium chloride (NH4Cl), and potassium cyanide (KCN) - the ammonium chloride serving as the source of ammonia.

In our card for Gabriel synthesis, we list all the reactants:

{{c1::Gabriel synthesis}} generates an amino acid from {{c2::potassium phthalimide}}, {{c2::diethyl bromomalonate}}, and {{c2::an alkyl halide}}.

I wonder if for consistency we should be doing the same for this card.

Another issue: The KA video above suggests that Strecker synthesis can occur using an aldehyde or ketone. Kaplan just states that an aldehyde is used. Have yet to see a question about this topic on UWorld. Non primary MCAT sources online seem to suggest a ketone can be used as well.

One thing that I think both the Gabriel Synthesis and Strecker synthesis cards are definitely currently lacking is that both produce a racemic mixture of L- and D-amino acid (Kaplan 10.2)

Action items:

  1. Aldehyde and ketone? or just aldehyde?
  2. Include all reactants to match depth provided by Gabriel synthesis card? (aldehyde/ketone/whatever we decide + Ammonia + KCN)
  3. Inclusion of racemic mixture of products?