[07.18.2024] Updated content, AnKing Step Deck/AnKingMed, ID 1868371

View Suggestion on AnkiHub

“Exceptions: sweat glands and arrector pili muscles (acetylcholine), adrenal medulla (80% epinephrine, 20% norepinephrine), renal arteries (dopamine)”
https://next.amboss.com/us/article/560ilS?q=ans#Yd27e4990202ef92bb0881345f11a4ff4

"Epinephrine
β > α (at high doses the α effect is predominant)
Stronger β2-receptor effect than norepinephrine

Norepinephrine
α1 > α2 > β1"
https://next.amboss.com/us/article/tN0X1g?q=ans#Y7edfeab56f1cf5a3f2b2f65c1d9403dd

@AnKing-Maintainers

The text specify alapha and beta receptor, so the answer ideally would be Norepi or epi

Sweat gland the action is on cholingergic receptor. Renal arteries the action is on D receptors

Can you clarify, I’m not fully following.

In the Amboss article it specifies that epinephrine acts at α1, α2, β1, and β2 receptors whereas norepinephrine does not really act at β2 receptors but does act at α1, α2, β1
https://next.amboss.com/us/article/tN0X1g?q=ans#Y7edfeab56f1cf5a3f2b2f65c1d9403dd

nid:1479351919381 is the companion flashcard and differentiates between norepinephrine and epinephrine. The key thing is the differentiation between β2.

I wasn’t aware that there was another card similar to this one

If I remember correctly, I don’t think post-ganglionic neurons release epinephrine, as this primarily comes from the adrenal gland. It doesn’t make sense to have it listed as a post-ganglionic neurotransmitter

So it seems like you’re saying the word “neurotransmitter” in the flashcard is the area that is of concern. Amboss just describes epinephrine as “A substance that is produced by the adrenal glands…” We could potentially change this flashcard to say “substance” or “hormone” instead of neurotransmitter.

In this Amboss article it does say epinephrine as a neurotransmitter is focused to CNS whereas norepinephrine is both CNS and postganglionic sympathetic synapses as a neurotransmitter.

https://next.amboss.com/us/article/lp0vpS?q=norepinephrine%20hormone#Yd628faa35916bf102dbad954b565bfb1