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Its on AMBOSS too but not sure if it’s important for USMLE
Loss-of-function mutations in the FLG gene lead to a deficiency of filaggrin, an epidermal protein that plays a role in the skin’s barrier function.
https://next.amboss.com/us/article/A40RNT?q=filaggrin#Z24a090fe307463199750760007c3888d
In UW I can say that each time filaggrin is mentioned, it 75% atopic dermatitis question and 25% icthyosis. (they have it in both tables)
In the deck it’s only mentioned twice “only ichthyosis”
Atopic dermatitis is one of the overlooked topics in the deck