@Anking-Maintainers
I support this change
got rejected a few times in the past due to poor rationale
Lack of edema doesn’t necessarily mean euvolemic though. Amboss and FAS1 don’t clearly state what the volume status is. The aldosterone escape mechanisms are activated through hypervolemia though so in order to be active they would require at least mild hypervolemia as a balance between aldosterone and escape mechanisms occur (ANP secretion and pressure naturesis both occur due to hypervolemia). Lots of UWorld QID tags on this card so someone with access could check them to see what UWorld says.
UpToDate: “aldosterone escape returns excretion to the level of intake and partially lowers the extracellular fluid volume toward normal”
UpToDate also mentions that “hypertension is a major clinical finding… dependent upon the mild volume expansion that occurs”
I think this is correct as well (see UW3 122706)
“Educational objective:
Primary hyperaldosteronism increases distal Nc reabsorption (secondary hypertension), leading to increased urinary excretion of and (metabolic alkalosis and hypokalemia). Overt volume overload is not seen due to aldosterone escape, and serum Na+ concentration is typically normal due to preserved antidiuretic hormone function.”