I agree with and/or change based on UW and AMBOSS.
(e.g. venlafaxine) is verbatim from AMBOSS and FA for Psych Clerkship resource (p. 52). But UW doesn’t specify venlafaxine anywhere I could find.
Interesting about the venlafaxine. I don’t have access to that FA resource. Does it state any reason behind why venlafaxine? I haven’t been able to find anything in AMBOSS regarding venlafaxine other than that it’s listed among examples of the SSRIs and SNRIs used to treat social anxiety disorder. It doesn’t seem, by my research, to be particularly “first-line” compared to the SSRIs
Yeah I don’t know either. It could be just side effect profiles / RCTs lean towards venlafaxine instead of duloxetine (the other SNRI). Could just be dogma. I can’t fathom that a question has both duloxetine AND venlafaxine as answer choices. Perhaps a quick UW check to make sure?
FA for the Psychiatry Clerkship p.52 discussing treatment for social anxiety disorder (social phobia): “First-line medication, if needed: SSRIs (e.g., sertraline, fluoxetine) or SNRIs (e.g., venlafaxine) for debilitating symptoms.”
FA for the Psychiatry Clerkship p.199 discussing pharmacology and SNRIs:
“[Venlafaxine is] often used for depressive disorders, anxiety disorders like generalized anxiety disorder (GAD), and neuropathic pain.”
“[Duloxetine is] often used for people with depression, neuropathic pain, and in fibromyalgia.”
Step2 UW 3839 - Vignette describes a patient with social anxiety disorder who is reluctant to consider psychotherapy. “Which of the following is the most appropriate pharmacotherapy?” Answer: Sertraline.
“Selective serotonin reuptake inhibitors (SSRIs) (eg, sertraline) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are used as first-line medication for social anxiety disorder. Cognitive-behavioral therapy is considered a first-line nonpharmacological treatment.”
Be gone with venlafaxine then. ![]()