system
April 16, 2024, 6:19pm
1
Jwill
April 16, 2024, 6:22pm
2
Here’s more of the content discussed on the other suggestion:
Also here is something: NCBI article " Calcium channels can be further subdivided into ligand gated or voltage gated . Voltage gated calcium channels can be characterized by high voltage (CaV1 L-type and CaV2 N, P/Q , and R-types) or low voltage (T-type)"
A suggestion was recently made bring up that cloze two of nid:1485127537767 was indistinguishable from Ethosuxamide.
nid:1485127537767
{{c2::Gabapentin}} is an anti-epileptic that exerts its effects by blocking voltage-gated {{c1::Ca2+}} channels
nid:1485127628996
Ethosuximide exerts its effects by blocking {{c1::T-type Ca2+::specific}} channels in the {{c2::thalamus}}
I feel like we could fix all these concerns by with the following simple changes
nid:1502344277221
Pregabalin is a gabapentinoid that works by binding the {{c2::α2δ}} subunit of high voltage gated {{c1::calcium}} channels
nid:1485127537767
{{c2::Gabapentin}} is an anti-epileptic that exerts its effects by blocking high voltage-gated {{c1::Ca2+}} channels
nid:1485127628996
is already very specific and clear and I don’t believe requires revision (but a clarifier could be added to the extra that “T-type are low voltage channels”)
Jwill
April 16, 2024, 6:23pm
3
@AnKing-Maintainers
Here are all three cards as part of a bulk suggestion.
Much appreciated - overall, I think these changes are unnecessary. Current versions seem fine to me, never had an issue.
Jwill
April 17, 2024, 5:23am
5
Yeah, I get that, I just feel like this might be the best way to resolve the N vs P/Q problem at least on this card. especially b/c it probably doesn’t actually warrant being closed given it’s not tested or emphasized anywhere.
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