AMBOSS agrees as well https://next.amboss.com/us/article/uJ0pDS?q=tumor+lysis+syndrome#Zfe45dd1efbd69bdc8eb20067a0ceeea4
“Allopurinol is not the drug of choice for established TLS because it does not influence the breakdown of uric acid that is already present.”
“Allopurinol Indicated as prophylaxis in patients at low to intermediate risk”
while rasbiurcase = Treatment of established TLS or Prophylaxis for intermediate to high-risk patients
think we should add this indication in extra, so allopurinol is not the drug of choice for ESTABLISHED TLS, if established, use rasburicase
I agree, but not sure how to edit my suggestion. Do you want me to resubmit?
Never mind, updated the suggestion
modified the card further to appropriately test these concepts. agree and approving