@AnKing-Maintainers
We already have a card covering systemic htn and OSA (which is due to increased sympathetic activation rather than nocturnal hypoxia)
Obstructive sleep apnea is associated with difficult to manage {{c1::systemic hypertension}} due to increased {{c2::sympathetic tone}}
I suggest we change card to what I have in image below instead. Not sure if “pulmonary vasoconstriction” will give the cloze away. If we feel like it will then just the change to extra should be good enough to clarify.
Amboss source
https://next.amboss.com/us/article/Lh0wef?q=obstructive+sleep+apnea
I’m not a fan of either original card to be honest. Isn’t the cause of the systemic hypertension ultimately the hypoxia too since that’s what causes the increased sympathetic tone? I think your suggestion is fine and would support it but I think for this one my preferred solution would just be to have in the main text that it causes ‘systemic hypertension’ with no close deletion around those two words and then ‘pulmonary hypertension’ in the cloze.
Kind of but AMBOSS is more specific. That’s why I changed the cloze 2 from hypoxia to “hypoxic pulmonary vasoconstriction”
AMBOSS quote
Obstruction of the upper airways → apnea → ↓ partial pressure of oxygen in arterial blood (PaO2), ↑ partial pressure of carbon dioxide in arterial blood (PaCO2, also known as hypercapnia), which leads to:
- ↑ Hypoxic pulmonary vasoconstriction → ↑ pulmonary hypertension → cor pulmonale
- ↑ Sympathetic activity → secondary hypertension
- Respiratory acidosis → renal compensation → increased HCO3 retention and decreased chloride reabsorption